Foundayo (orforglipron) received FDA approval on April 1, 2026. It's the first oral GLP-1 you can take any time of day without food or water restrictions. Self-pay starts at $149/month; insured patients may pay $25/month with a savings card.
How to Get Prescribed
Foundayo prescriptions are available through your existing doctor, telehealth platforms, LillyDirect, and retail pharmacies nationwide. The eligibility criteria are standard: BMI 30+ or BMI 27+ with at least one weight-related condition.
What Makes It Different
| Feature | Foundayo | Injectable GLP-1s |
|---|---|---|
| Administration | Daily pill, any time | Weekly injection |
| Food restrictions | None | N/A |
| Avg weight loss | ~11-12% | 15-21% |
| Self-pay | $149-399/mo | $99-1,349/mo |
| Refrigeration | No | Yes (injectable) |
The Titration Schedule
Foundayo follows a structured dose escalation: 0.8mg → 2.5mg → 5.5mg → 9mg → 14.5mg → 17.2mg, increasing approximately every 4 weeks. Most patients reach their maintenance dose within 4-6 months.
Who It's Best For
Foundayo is ideal if you strongly prefer pills over injections, have commercial insurance (savings card brings cost to $25/mo), want an FDA-approved medication with standardized manufacturing, or travel frequently and can't manage cold-chain shipping for injectables.
If maximum weight loss is your priority and cost is secondary, injectable semaglutide or tirzepatide through telehealth remains more effective.
Sesame Care From $99/visit · Prescribes FDA-approved brand-name medications only. Accepts insurance. No subscription lock-in.
Prescribes FDA-approved brand-name medications only.
⚕️ Compounded medications are not FDA-approved. They are prepared by licensed pharmacies under physician supervision.